How do we reopen our motility laboratory safely and efficiently?

How do we safely get people to stop smoking?

Nicotine replacement therapy (NRT) is a valuable, proven, and U.S. Food and Drug Administration-approved tool for smoking cessation. However, the discoveries of functional nicotinic acetylcholine receptors (nAChR) on lung epithelial and cancer cells and of nAChR polymorphisms associated with lung cancer risk, in addition to a large number of preclinical studies indicating that nicotine may prom...

How to Encode Polymorphic Types Safely and Efficiently

Most automatic theorem provers are restricted to untyped or monomorphic logics, and existing translations from polymorphic logics are either bulky or unsound. Recent research shows how to exploit monotonicity to encode ground types efficiently: monotonic types can be safely erased, while nonmonotonic types must generally be encoded. We extend this work to rank-1 polymorphism and show how to eli...

How do we know the value of our research?

R esearch is vital to the progress of medicine. Patients depend on it to generate new knowledge that may improve their lives. Clinicians yearn for more effective tools and better guidance for themselves and their patients. Funders seek a substantial return on their investment, often in the form of a contribution to society. Researchers want their work to result in meaningful benefits for others...

Leadership to transform practice: how do we wear our words?

How do we keep our residents safe? An educational intervention.

OBJECTIVE Recent evidence suggests that 25-64 % of psychiatry residents are the victims of assault by patients; only a minority, however, feel they receive adequate safety and violence training during residency. To address this disparity, the author designed, implemented, and assessed the effectiveness of a brief educational intervention focused on improving the residents' ability to recognize ...